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博士生导师

张薇

主任医师
博导
个人简介 学术论文 科研项目

医学博士,山东大学齐鲁医院心内科主任医师,二级岗位教授,博士生导师,享受国务院政府特殊津贴专家,山东省有突出贡献的中青年专家。主要从事内科学心血管病专业的基础与临床工作,专业知识全面,临床经验丰富,在电生理检查、经导管射频消融、超声心动图诊断和危重病例抢救等方面具有高深的造诣,是国家重点学科山东大学内科学(心血管病学)的主要学术带头人之一,是山东大学齐鲁医院心内科电生理专业学术带头人。作为第一负责人,已承担国家自然基金、教育部基金、山东省自然基金、山东省科委和卫生厅项目多项,目前在研课题国家自然基金2项,省级课题2项。在国内外医学期刊上发表文章100余篇,获国家科技进步三等奖、教育部科技进步二等奖、山东省科技进步一等、二等、三等奖和山东省自然科学二等奖20余项。


1. Tang M, Zhong M, Shang Y, Lin H, Deng J, Jiang H, Lu H, Zhang Y, Zhang W. Differential regulation of collagen types I and III expression in cardiac fibroblasts by AGEs through TRB3/MAPK signaling pathway. Cell Mol Life Sci. 2008 Sep;65(18):2924-32. (IF=6.721)

2. Gong HP, Wang ZH, Jiang H, Fang NN, Li JS, Shang YY, Zhang Y, Zhong M, Zhang W. TRIB3 functional Q84R polymorphism is a risk factor for metabolic syndrome and carotid atherosclerosis. Diabetes Care. 2009 Jul;32(7):1311-3. (共同通讯,IF= 13.397)

3. Ti Y, Xie GL, Wang ZH, Bi XL, Ding WY, Wang J, Jiang GH, Bu PL, Zhang Y, Zhong M, Zhang W. TRB3 Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model. Diabetes. 2011; 60(11):2963-74. (共同通讯,IF=7.273)

4. Wang ZH, Shang YY, Zhang S, Zhong M, Wang XP, Deng JT, Pan J, Zhang Y, Zhang W. Silence of TRIB3 Suppresses Atherosclerosis and Stabilizes Plaques in Diabetic ApoE-/-/LDLR-/- Mice. Diabetes. 2012 Feb;61(2):463-73. (IF=7.273)

5. Li Y, Ding W, Wang H, Song N, Lin L, Wang Z, Zhong M, Zhang Y, Zhang W. Relationship of CHA2DS2-VASc and CHADS2 Score to Left Atrial Remodeling Detected by Velocity Vector Imaging in Patients with Atrial Fibrillation. PLoS One. 2013;8(10):e77653

6. Ding WY, Liu L, Wang ZH, Tang MX, Ti Y, Han L, Zhang L, Zhang Y, Zhong M, Zhang W. FP-receptor gene silencing ameliorates myocardial fibrosis and protects from diabetic cardiomyopathy. J Mol Med. 2014;92(6):629-40.

7. Ding WY, Li WB, Ti Y, Bi XP, Sun H, Wang ZH, Zhang Y, Zhang W, Zhong M. Protection from renal fibrosis, putative role of TRIB3 gene silencing. Exp Mol Pathol. 2014;96(1):80-4.

8. Wang J, Han L, Wang ZH, Ding WY, Shang YY, Tang MX, Li WB, Zhang Y, Zhang W, Zhong M. Overexpression of STAMP2 suppresses atherosclerosis and stabilizes plaques in diabetic mice. J Cell Mol Med. 2014;18(4):735-48.

9. Fu KL, Fan GQ, Han L, Wang XZ, Wang J, Wang YS, Zhong M, Zhang Y, Zhang W, Wang ZH. Impact of type 2 diabetes mellitus on hospitalization costs in older patients with acute myocardial infarction. Clin Interv Aging. 2014;9:711-8.

10. Fan GQ, Fu KL, Jin CW, Wang XZ, Han L, Wang H, Zhong M, Zhang Y, Zhang W, Wang ZH. A medical costs study of older patients with acute myocardial infarction and metabolic syndrome in hospital. Clin Interv Aging. 2015;10:329-37.

11. Peng J, Zhao Y, Zhang H, Liu Z, Wang Z, Tang M, Zhong M, Lu F, Zhang W. Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure. Hypertens Res. 2015;38(2):123-31.

12. Zhang L, Ding WY, Wang ZH, Tang MX, Wang F, Li Y, Zhong M, Zhang Y, Zhang W. Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy. J Transl Med. 2016;14(1):109.

13. Wang F, Han L, Qin RR, Zhang YY, Wang D, Wang ZH, Tang MX, Zhang Y, Zhong M, Zhang W. Overexpressing STAMP2 attenuates adipose tissue angiogenesis and insulin resistance in diabetic ApoE-/-/LDLR-/- mouse via a PPARγ/CD36 pathway. J Cell Mol Med. 2017;21(12):3298-308.

14. Li Y, Yan H, Wang F, Huang S, Zhang Y, Wang Z, Zhong M, Zhang W. Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice. Biochem Biophys Res Commun. 2017;486(3):693-9.

1. PTPN2介导脂肪组织免疫T细胞极化在2型糖尿病动脉粥样硬化易损斑块形成中的作用. 国家自然基金

2. 内皮间质转化在2型糖尿病支架内再狭窄中的作用机制研究. 国家自然基金

学会任职情况:目前,山东省心血管分会副主任委员;中国农村卫生协会高血压专业分会常委;中国医师协会高血压专家委员会委员;中国医师协会心血管内科医师分会女医师工作委员会委员;中华医学会心血管分会女性心脏健康学组委员;中国女医师学会理事、山东省心电生理与起搏专业委员会副主任委员等职务。